The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load
Status:
Recruiting
Trial end date:
2021-06-30
Target enrollment:
Participant gender:
Summary
Preoperative antiseptic mouth rinses have been widely used as a standard protocol before
routine dental treatment reduces oral microorganism counts. During dental procedures,
aerosolized microorganisms contaminate the dental environment and nearby surfaces and remain
suspended for 4 hours. Thus, the reduction in the number of aerosolized microorganisms by
pre-procedural rinsing may reduce cross-contamination between dentists, office personnel, and
patients. Recent reviews have advocated the use of preoperative rinsing to control and reduce
the risk of SARS-CoV-2 transmission. However, no clinical studies have been done yet to
support the effectiveness of any pre-procedural oral rinses against SARS-CoV-2. The proposed
study will mitigate the spread of COVID-19 disease in dental health care facilities and
ensure the patients' good health and healthcare workers. The purpose of this clinical trial
is to determine and compare the effectiveness of four commercially available, pre-procedural
mouth rinses versus distilled water on viral load of SARS-CoV-2 found in the saliva of
COVID-19 positive patients and to measure the pre-rinsing viral load with the post-rinsing at
three-time points.