The Efficacy of Nasal Steroids in Treatment of Otitis Media With Effusion: Acomparative Study
Status:
Unknown status
Trial end date:
2020-03-01
Target enrollment:
Participant gender:
Summary
Otitis media with effusion (OME) is defined as effusion in the middle ear without signs and
symptoms of an acute infection. It is a leading cause of hearing impairment in children, and
its early and proper management can avoid hearing and speech impairment, which can cause
developmental delay in children.Although many conditions such as enlarged adenoids, cleft
palate, Down syndrome, Kartagener syndrome, and nasopharyngeal neoplasm are related to the
role of eustachian tube (ET) dysfunction in the pathogenesis of OME, allergic, immunologic,
and infectious factors have also been claimed. Treatment of OME is still a controversial
issue, as conventional treatment approaches fail to provide satisfactory and permanent relief
of otologic symptoms.There is lack of proven effectiveness of the commonly given treatments,
such as antibiotics, decongestants, and antihistamines, which are potentially harmful and
have disadvantages. Few in those studies,investigated topical intranasal steroid for OME
treatment,and in those studies, the duration of intranasal steroid application was short and
there was no hearing evaluation.