The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty
Status:
Recruiting
Trial end date:
2021-02-01
Target enrollment:
Participant gender:
Summary
This prospective, double-blinded, randomized controlled study evaluates the effects of
peripheral nerve blocks with and without local infiltration analgesia for postoperative pain
management after primary total knee arthroplasty. There are no any studies that show the
demand for local infiltration analgesia when together peripheral nerve blocks are performed.
Patients undergoing primary total knee arthroplasty will be randomly assigned to receive
local infiltration analgesia with or without (placebo group) local anesthetic. All patients
will receive peripheral nerve blocks for postoperative analgesia: femoral triangle and distal
adductor canal blocks. Comparison of these two groups of patients will be based on the
effects on postoperative pain control, the extent of motor blockade, the ability of early leg
motion and ambulation, patients satisfaction rates over the time of clinical recovery.
Consequently, the investigators hypothesized that peripheral nerve blocks (femoral triangle
and distal adductor canal blocks) with and without local infiltration analgesia provide
similar postoperative pain relieving effects and the ability of early mobilization after
total knee arthroplasty.
Phase:
N/A
Details
Lead Sponsor:
Lithuanian University of Health Sciences
Treatments:
Anesthetics Anesthetics, Local Bupivacaine Epinephrine Epinephryl borate Pharmaceutical Solutions Racepinephrine