The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy
Status:
Unknown status
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
Retinal nonperfusion drives vision-threatening complications such as pathological
neovascularization, which can lead to neovascular glaucoma, vitreous hemorrhage, or
tractional retinal detachments and macular edema in diabetic retinopathy. Thus, decreasing
nonperfusion area with aid of anti-VEGF agents might be a useful way to prevent deteriorating
course of diabetic retinopathy. The main purpose of this study is to determine the efficacy
of intravitreal aflibercept injection in improvement of retinal nonperfusion and identify
associated factors in patients with nonproliferative diabetic retinopathy with moderate
retinal nonperfusion.