The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars

• Status: Unknown status
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Our study involves the evaluation of a high potency chemical peel in its efficacy and safety profile for the treatment of acne scars. This chemical peel regime is a high potency peel of 70% glycolic acid combined with vitamin C that is purported to provide a good balance between yielding results and patient safety. We aim to evaluate its efficacy and safety profile of a single application. The study design is based on a single group that compares pre- vs post-intervention. 10 patients with atrophic acne scars of skin type I-IV will be recruited. Potential benefits include improvement of post acne scars with a short downtime and risks include post peel hyper pigmentation and scarring. We believe that this treatment will be highly beneficial to patients with post acne scarring.

This chemical peel regime has good efficacy and safety profile for the treatment of acne scars.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National University Hospital, Singapore
• Treatments: Ascorbic Acid; Glycolic acid

Criteria

Inclusion Criteria:

1. Atrophic scars

2. Skin type I to IV

Exclusion Criteria:

1. Pregnancy, breastfeeding

2. Active dermatitis (on the face), rosacea, allergic rhinitis, active herpes simplex

3. Known hypersensitivity

4. Previous keloids

5. Laser ablative procedures within the last month

6. Chemical peels within the last 6 months

7. Used oral retinoids in the past 6 months

8. Used topical retinoids in the past one week

9. Used scrub, AHA, skin irritant for the past 24h

10. Presence of facial warts or fungal infections

11. Photoallergies

12. Prior poor reaction to a chemical peel

13. Radiotherapy

14. Skin type V and VI

15. Patients with predominantly ice pick and boxcar scars