The Efficacy and Safety of Topical Papaya (Carica Papaya) Leaf Extract 1% Ointment Versus Mupirocin 2% Ointment in the Treatment of Limited Impetigo: a Randomized, Double-blind, Controlled Clinical Trial

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study will be an investigator-blinded, patient-blinded, assessor-blinded, parallel-group, randomized clinical trial. It aims to evaluate the efficacy of one-week twice-daily application of topical papaya leaf extract ointment compared to mupirocin ointment in achieving clinical cure among patients with impetigo.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Philippine Dermatological Society
• Collaborator: St. Luke's Medical Center
• Treatments: Mupirocin

Criteria

Inclusion Criteria:

• Healthy Filipino patients aged 1 year and above with primary impetigo, limited to less than or equal to 1% BSA, and involving only one body area

Exclusion Criteria:

• Extensive impetigo (>1% BSA), affecting more than one body area

• Systemic involvement (lymphadenopathy, fever, sepsis)

• Chronic comorbidities like diabetes mellitus, malignancy, chronic venous insufficiency

• Concurrent immunosuppressive therapy

• Patients ≤ 1 year

• Pregnant & lactating patients