The Efficacy and Safety of Combined Therapy With Red Yeast Rice and Low-dose Statin：Comparing With Standardized Statin
Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
Double-dose statin regimen achieves merely 6% of decrease in low-density lipoprotein
cholesterol (LDL-C) levels, whereas the risk of side effects increased largely. The
investigators' previous pilot study (NCT01686451) has suggested that red yeast rice was of
similar lipid-lowering efficacy while was associated with less fatigue than statins. The
purpose of this study is to evaluate the efficacy and safety of combined therapy with red
yeast rice and low-dose atorvastatin in persons with mild atherosclerotic cardiovascular
disease and who qualified for statin therapy according to national guidelines.