In this study the influence of zonisamide administration over a 13 week period on alcohol
consumption in alcoholic (alcohol dependent) subjects will be examined. The dose of
zonisamide given to subjects will be slowly increased over a period of several weeks. They
will receive a full dose over a 5 week period. This will be a pilot study in which all of the
subjects will only receive zonisamide. A primary objective of this study is to determine the
possible size of the effect that zonisamide administration has on drinking (i.e. drinks
consumed per day) to allow us to plan for a larger clinical trial of the effects of
zonisamide on alcohol dependence.