The Effects of Trichosanthes Root on Blood Sugar in Patients With Diabetes Mellitus
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Diabetes mellitus (DM) locates fifth of ten leading death etiology, the population of
diabetic patients has a tendency of increase. Trichosanthes root is called as Tian Hua Fen,
According to traditional Chinese writing record that Trichosanthes root has the action of
downbear fire, moisten dryness, and slippery phlegm, and release thirst. The Trichosanthes
root may lower blood sugar levels in the modern study. The investigators designed a double
blind, randomized controlled study, a total of 60 diabetic patients with high blood sugar
were divided into treatment and control groups, and each group was 30 patients. In the
treatment group, oral administration of Trichosanthes root 1.5 g, bid/day for 84 days
continuously; in the control group, oral administration of Trichosanthes root placebo 1.5 g,
bid/day for 84 days continuously. The main outcome measure was the changes of plasma blood
sugar and Glycated hemoglobin A1c (HbA1c) levels changed before and after Trichosanthes root
treatment. The investigators predict the results of the present study indicated that
Trichosanthes root can improve plasma blood sugar and glycated hemoglobin A1c levels.