The Effects of Sex Hormones on Cognition and Mood in Older Adults

• Status: Terminated
• Trial end date: 2005-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is investigating the effects of hormone replacement therapy on memory, mental abilities and mood in older adults aged 65-90. During the nine month long study, men will take testosterone for three months and women will take estrogen for three months. At four points during the study (once every three months), participants will complete a test battery and have blood drawn.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Aging (NIA)
• Treatments: Estrogens; Testosterone

Criteria

Inclusion Criteria:

• Women and men aged 65-90 who have not received hormone replacement for the last three months.

Exclusion Criteria:

• Previous head injury with loss of consciousness for more than one hour.

• Men with a history of prostate cancer.

• Men on testosterone replacement within the past three months.

• Women with a history of breast or uterine cancer.

• Women on estrogen replacement within the past three months.