The Effects of Nutrition Supplementation and Resistance Exercise During Hemodialysis

• Status: Completed
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: All

Summary

To test the hypothesis that an exercise session combined with adequate nutritional supplementation improves skeletal muscle protein accretion during a hemodialysis session.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vanderbilt University; Vanderbilt University Medical Center

Criteria

Inclusion Criteria:

• On hemodialysis for more than 3 months, on a thrice weekly hemodialysis program.

• Adequately dialyzed (Kt/V > 1.2).

• Age 18-75

Exclusion Criteria:

• Pregnant women.

• Patients unable to perform exercise

• Severe unstable underlying disease besides commonly associated with ESRD. Cardiac patients that are stable will be included.

• Patients hospitalized within the last month prior to the study.

• Patients with malfunctioning arterial-venous access (recirculation and/or blood flow < 750 ml/min)

• Patients receiving steroids and/or other immunosuppressive agents.