The Effects of Neprilysin on Glucagon-like Peptide-1

• Status: Completed
• Trial end date: 2019-05-14
• Target enrollment: 0
• Participant gender: Male

Summary

In the current study we wish to investigate the effects on glucagon-like peptide-1 (GLP-1) of a neprilysin inhibitor

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Nicolai Jacob Wewer Albrechtsen
• Treatments: Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucagon-Like Peptide 1; LCZ 696; Sacubitril and valsartan sodium hydrate drug combination; Sitagliptin Phosphate

Criteria

Inclusion Criteria:

• men

• body mass index between 20-25

Exclusion Criteria:

• acute diseases within the two weeks

• chronic diseases

• smoker

• alcoholism, drug addiction or recent weight loss

• blood donation within the last 3 months