The Effects of Nebivolol on the NO-system in Patients With Essential Hypertension
Status:
Completed
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
Investigators want investigate the following hypothesis:
1. Nebivolol increases nitric oxide activity in the systemic circulation and the kidney
2. The increased activity of nitric oxide during nebivolol treatment can be demonstrated by
inhibition of NO synthesis with L-NMMA. We expect increased responses in blood pressure
and sodium excretion is expected during nebivolol treatment compared to placebo.