The Effects of Lidocaine and Esmolol on Attenuation of Hemodynamic Response to Orotracheal Intubation

• Status: Unknown status
• Trial end date: 2019-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The present study aims to compare the hemodynamic response during laryngoscopy and orotracheal intubation using continuous infusion of lidocaine and esmolol in patients undergoing general anesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital de Base
• Treatments: Anesthetics; Anesthetics, Local; Esmolol; Lidocaine

Criteria

Inclusion Criteria:

• Patients aged between 18 and 70 years

• Physical State 1, 2 or 3 of the American Society of Anesthesiology (ASA)

• Electively or urgently scheduled for surgery requiring general anesthesia, with programming of orotracheal intubation via direct laryngoscopy at the Base Hospital of the Federal District.

Exclusion Criteria:

• Patients younger than 18 and over 70 years of age

• Patients with contraindications or history of hypersensitivity to the drugs involved in the study

• Patients with coronary ischemic disease

• Patients with atrioventricular block at any grade

• Patients with diagnosed cardiac arrhythmias

• Patients with heart failure

• Patients who are beta-blockers or calcium channel blockers

• Patients with renal insufficiency of any kind

• Patients with difficulty predicting orotracheal intubation

• Patients with BMI ≥ 35 kg / m²

• Patients who underwent neuroaxis block before anesthetic induction

• Patients who refuse to participate in the study after submitting the informed consent form

• Patients requiring two or more attempts of laryngoscopy for positioning of the orotracheal tube

• Patients with asthma

• Any other condition that, in the opinion of the researcher, may pose a risk to the patient or interfere with the objectives of the study