The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells
Status:
Completed
Trial end date:
2018-06-28
Target enrollment:
Participant gender:
Summary
We will investigate whether human endotoxemia induces changes in human bone marrow cells and
their downstream effector cells. To comprehensively investigate underlying mechanisms behind
functional and transcriptional changes in these cell types, we will use state-of-the-art
systems biology techniques, including single cell transcriptomics (epi)genetics, and
metabolomics.