The Effects of Height and Weight Adjusted Dose of Local Anesthetic.
Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
At our centre a conventional dose of 12 mg of hyperbaric bupivacaine in combination with a
short acting opioid fentanyl (to increase block density) and a long acting opioid morphine
(to provide post-operative pain relief ) is used for spinal anesthesia for cesarean
section.However, larger doses of local anesthetic drug when used in caesarean section
commonly cause low blood pressure and requires drugs (vasopressors) to treat it. In our study
the investigators will standardize the doses of both opioids (fentanyl/morphine) and adjust
the dose of local anesthetic (bupivacaine) based on the patients height and weight .One of
the obvious challenges anesthesiologists face is providing adequate anesthesia to the patient
whilst minimizing harmful side effects. Our primary concern is the low blood pressure as an
effect of the spinal anesthetic as it is harmful to both mother and the baby. The
investigators propose that the extent of surgical anesthetic block, which is dependent on
height and weight in our adjusted dose group, will provide adequate anesthesia for surgery
and minimise maternal low blood pressure.
Phase:
N/A
Details
Lead Sponsor:
Lawson Health Research Institute
Treatments:
Anesthetics Anesthetics, Local Ephedrine Oxymetazoline Phenylephrine Pseudoephedrine