The purpose of this study is to evaluate the effects of a single low dose of the D2/D3
antagonist amisulpride on reward processing. More generally, this study will test the role of
dopamine (a naturally occurring brain chemical) in depression.
Hypotheses:
Administration of a single low dose of the D2/D3 antagonist amisulpride will (1) improve
performance in a behavioral task assessing learning from feedback and (2) boost activation in
reward-related brain regions.