The Effects of Cannabidiol on the Driving Ability of Healthy Adults
Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
A randomized, parallel-group, double-blind, exploratory two-arm trial to assess the effects
of CBD on driving ability along with changes in psychological status (i.e. mood, drowsiness,
sedation) and cognitive function. Forty healthy West Virginia University (WVU) students will
be allocated and randomized to receive: (1) 300 mg of pure CBD oil or (N=20) (2) placebo
matched in appearance and taste (N=20). After consuming the study drug, each individual will
participate in a 25-35-minute driving simulation and their driving performance measured. To
assess changes in psychological status (i.e. mood, drowsiness, sedation) and drug
impairment-related cognitive function, the Visual Analog Mood Scale, Stanford Sleepiness
Scale , Digital Symbol Substitution Test, Trail Making Test Part A and B, Psychomotor
Vigilance Test, and Simple Reaction Time test will also be administered to participants at
baseline (prior to study drug consumption) and following completion of the driving simulation
test. The entire protocol will be completed in one day and should take 4-4.5 hours to
complete for each participant.