The Effects of Beclomethasone Upper the Endotracheal Cuff on the Occurrence of Sore Throat at Extubation

• Status: Withdrawn
• Trial end date: 2017-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to test the effectiveness of a solutions of beclomethasone repeatedly instilled through the supraglottic line of the endotracheal tube on post-extubation airway disturbances related to tracheal intubation. The primary endpoint will be the decrease of the incidence of sore-throat 15 minutes and 12 hours after extubation. Secondary endpoints will regard the effects on hoarseness and cough.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Policlinico Universitario Agostino Gemelli
• Treatments: Beclomethasone

Criteria

Inclusion Criteria:

• intensive care postoperative admission

• tracheal intubation for a total lapse of time between 10 and 18 hours

Exclusion Criteria:

• age < 18,

• hypersensitivity to FANS and/or corticosteroids,

• a medical history positive for diseases affecting upper airways or trachea or causing cough, hoarseness, or voice disorders;

• intubation after more than two attempts or with aids (i.e. stylets, Airtraq, Glidescope, Fibroscopy).