Overview

The Effects of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Blepharitis During a Four-Week Treatment Period (P08638)

Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
0
Participant gender:
All
Summary
The objective of this study is to compare the safety and efficacy of azithromycin ophthalmic solution, 1% versus placebo over a four-week treatment period.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Merck Sharp & Dohme Corp.
Treatments:
Azithromycin
Ophthalmic Solutions
Pharmaceutical Solutions
Criteria
Inclusion Criteria:

- Have best corrected visual acuity in both eyes of at least +0.7 or better

- If female, are non-pregnant or non-lactating

- Have a current diagnosis of blepharitis in one or both eyes

Exclusion Criteria:

- Have lid structural abnormalities

- Have suspected ocular fungal or viral infection

- Have practiced warm compress therapy within 14 days prior to Visit 2

- Unable to withhold the use of contact lenses during the treatment or follow-up periods

- Unable to withhold the use of ocular cosmetic products within 24 hours prior to study
visits

- Have had penetrating intraocular surgery within 90 days prior to Visit 2

- Have had ocular surface surgery within the past year prior to Visit 2

- Have a serious medical condition which could confound study assessments