The Effects of Active VItamin D on Left Atrial Volume Index
Status:
Withdrawn
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
This is a pilot feasibility study to determine the effects of an activated vitamin D compound
(paricalcitol) on heart structure (size) and function (ability to relax) in patients with
normal kidney function and a form of heart failure known as HFPEF (heart failure and
preserved ejection fraction). This study will also examine heart failure-related
hospitalizations and changes in cardiac-stretch and biological markers that are believed to
change along with heart size. Patients in this pilot study will be treated for a period of 48
weeks with paricalcitol at a dose previously approved by FDA (1 mcg per day) and followed-up
for 4 weeks after treatment is completed.