The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

• Status: Completed
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess if ketamine will induce, in healthy volunteers, impairment of working memory and if the drug AZD8529 will block the effects of ketamine on working memory as assessed by functional magnetic resonance imaging (fMRI).

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: AstraZeneca
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• Right handed

• 12th grade education or equivalent

• Able to read and write English as primary language

Exclusion Criteria:

• History of head injury

• Substance abuse or dependence

• History of claustrophobia