The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

• Status: Unknown status
• Trial end date: 2019-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Surgical-site infection is the most commonly reported nosocomial infection in patients undergoing surgery and 3rd most nosocomial infection in hospitalized patients. The SSI is associated with increases of length of hospitalization for 6 days and increases the hospital's cost by $ 300.

Because of these, prevention of SSI with appropriate antibiotic is essential.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Isfahan University of Medical Sciences
• Treatments: Cefazolin; Vancomycin

Criteria

Inclusion Criteria:

• age 18 years and above

• elective surgical patients

• No pre-surgery infection

• Do not use antibiotics before surgery

• Insensitivity to beta-lactam antibiotics

Exclusion Criteria:

• cranioplasty

• Failure to follow the patient

• The patient's unwillingness to continue participating in the research project

• Death of the patient