The Effectiveness of GM-CSF in HIV-Positive Patients Who Are Also Receiving Anti-HIV Therapy
Status:
Completed
Trial end date:
2003-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see how HIV-positive patients who are taking anti-HIV drugs
and have a viral load (level of HIV in the blood) of 1,500 copies/ml or more respond to
GM-CSF (granulocyte-macrophage colony-stimulating factor).
GM-CSF is a medication that is being tested in HIV-positive patients to see if it can improve
their immune systems or if it can lower the level of HIV in their blood. GM-CSF is often
given to patients with leukemia or patients who have received bone marrow transplants to
increase their white blood cells and to improve their immune systems. Doctors believe that
GM-CSF can increase CD4 counts in HIV-positive patients, but this study will also look at how
GM-CSF affects viral load.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)