The Effectiveness and Safety of Gabapentin for Post-operative Pain After Cesarean Section

• Status: Terminated
• Trial end date: 2009-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether a single dose of gabapentin, given before cesarean section, will reduce pain in the initial 24 hours after surgery. Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of surgeries. We believe that it may be effective for treating pain after cesarean sections, but it has never been studied for this purpose.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• Women undergoing elective cesarean delivery

Exclusion Criteria:

• Patients unable to communicate in English

• Patients with an American Society of Anesthesiologists (ASA) classification of 3 or higher

• Patients with contraindications to any of the medications used in the study

• Patients with contraindications to spinal anesthesia

• Patients who have taken any pain medication in the past week

• Patients with fetuses having congenital abnormalities

• Patients with severe mental disorders

• Patients with HIV or hepatitis infections

• Intravenous drug users

• Patients with uncontrolled hypertension and diabetes

• Patients with central nervous system tumours