The Effect on EPCs by Statin Loading in "All Comers" With an ACS
Status:
Completed
Trial end date:
2017-09-25
Target enrollment:
Participant gender:
Summary
Cardiovascular disease is a major cause of morbidity and mortality worldwide. There are a
number of risk factors for coronary artery disease and all to often patients admitted with an
acute coronary syndrome have these comorbidities.
The main stay of treatment of such patients is to perform coronary angiography and if
required coronary angioplasty.
Previous studies have shown a link between endothelial progenitor cell (EPC) count, coronary
artery disease and statin therapy or loading, however these studies have excluded patients
with significant comorbidities and therefore have not truly represented "real life" patients.
This pilot study will assess EPC response in patients that are able to undergo coronary
intervention as part of their normal clinical management under current guidelines regardless
of pre-existing comorbidities. The research team believe this will allow representation of
"real world" patients.