The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI

• Status: Completed
• Trial end date: 2019-05-22
• Target enrollment: 0
• Participant gender: All

Summary

Evaluating whether forced diuresis with matched hydration will reduce the risk of contrast induced nephropathy in patients undergoing Transcatheter Aortic Valve Implantation (TAVI).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tel-Aviv Sourasky Medical Center
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

1. Subject is 65 years old who is able and willing to give an informed consent.

2. Patients undergoing planned trans-femoral TAVI.

3. Calculated eGFR below 60ml/min/1.73m2 (MDRD)

Exclusion Criteria:

1. History of acute coronary syndrome in the past 30 days.

2. History of congesting heart failure with left ventricular ejection fraction <30% or exacerbation in the past 30 days.

3. Current dialysis treatment.

4. Known furosemide hypersensitivity.

5. Contraindications to placement of a Foley catheter in the bladder.