The Effect of Zinc on the Gingival Crevicular Fluid Level of Total Oxidant Capacity in Type 2 Diabetic Patients

• Status: Unknown status
• Trial end date: 2020-08-30
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the effect of systemic administration of zinc on the gingival crevicular fluid level of total oxidant capacity in controlled Type-2 diabetic patients with stage-II and III periodontitis after non-surgical periodontal therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Zinc; Zinc Sulfate

Criteria

Inclusion Criteria:

• Controlled Type-2 diabetes mellitus

• Stage-II &III periodontitis

• At least 2 sites with clinical attachment loss 3 or 4 mm to ≥5 mm and radiographic bone loss 15% Extending to mid-third of root and beyond.

• Probing depth from ≤5 mm to ≥6 mm

Exclusion Criteria:

• Any periodontal or Antibiotic treatment during the last six months.

• Receiving trace element supplements in the previous three months

• Pregnant or lactating females

• Gastric or diuretic treatment

• Acute renal failure

• smoking