The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain

• Status: Unknown status
• Trial end date: 2020-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed as a population-based prospective randomized cohort study. A prospective cohort of patients admitted to laparoscopic sleeve gastrectomy due to morbid obesity

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Soroka University Medical Center
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Age ≥18 years

• Patients admitted for laparoscopic sleeve gastrectomy

• Elective surgery

• BMI > 40

• American Society of Anesthesiology Classification: 1-2

Exclusion Criteria:

• Patients' refusal to participate in the study

• Patients unable to give an informed consent

• Pregnancy

• Emergency surgery

• Patient with known allergy to paracetamol

• Patient with hepatic failure

• international normalized ratio >1.7

• Albumin<3.5g/Dl

• Bilirubin >2mg/dL

• Patient with fever > 37.5 ° C

• Patient with hemoglobin < 8

• Patients chronically treated with steroids or steroid-treated patients over a month in the year preceding surgery.

Drug addict