The Effect of Thiamine vs. Placebo on VO2 in Critical Illness
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to determine the effect of thiamine therapy on oxygen
consumption (VO2) in critically-ill patients. We will evaluate this by measuring VO2 before
and after thiamine or placebo administration in patients admitted to the ICU and requiring
mechanical ventilation. A secondary aim is to evaluate the effect of thiamine vs. placebo on
the metabolic profile of the patients.