Overview

The Effect of Theophylline in the Treatment of Bronchiectasis

Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
0
Participant gender:
All
Summary
Theophylline was well recommended in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. However, there is no supporting evidence for their efficacy in the treatment of bronchiectasis. Our hypothesis is that theophylline will play a role in bronchiectasis. Our purpose is to examine the efficacy and safety of 24 weeks treatment with theophylline in subjects with non-cystic fibrosis bronchiectasis.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
The First Affiliated Hospital of Guangzhou Medical University
Treatments:
Theophylline
Criteria
Inclusion Criteria:

- Patients between 18-70 years old with non-CF bronchiectasis ,free from acute
exacerbations for at least 3 months.Stable phase of the disease.

Exclusion Criteria:

- Patients with a cigarette smoking history of more than 10 packs-year. Patients with
COPD. Patients with traction bronchiectasis due to advanced fibrosis. Patients with
known intolerance for theophylline. Patients with asthma. Patients with other disease
disturbing outcomes of the trials. Patients without consent.