Overview

The Effect of Testosterone on Mood and Quality of Life

Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
We hypothesize that testosterone replacement will improve mood and quality of life in older men with low testosterone and mild depression. Study subjects will receive either testosterone gel or a placebo (inactive) gel for 12 weeks. Neither the subject or the investigator will know whether they are receiving placebo or testosterone gel. At the end of the initial 12 week period, all subjects will receive testosterone gel for 12 more weeks. Mood and quality of life measures will be obtained at baseline, at the end of the double-blind phase and at the end of the extension phase (when all subjects receive testosterone.)
Phase:
N/A
Details
Lead Sponsor:
Seattle Institute for Biomedical and Clinical Research
Collaborators:
American Federation for Aging Research
Geriatric Research Education and Clinical Care
Solvay Pharmaceuticals
University of Washington
VA Puget Sound Health Care System
Treatments:
Methyltestosterone
Testosterone
Testosterone 17 beta-cypionate
Testosterone enanthate
Testosterone undecanoate