Overview

The Effect of Sumatriptan and Placebo on Isosorbide-5-mononitrate Induced Headache

Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers and in patients with migraine without aura with a long lasting Nitrogen Oxide (NO) donor. If the headache responds to sumatriptan, the model can be used to test new drug candidates.
Phase:
N/A
Details
Lead Sponsor:
Danish Headache Center
Treatments:
Isosorbide
Isosorbide Dinitrate
Isosorbide-5-mononitrate
Sumatriptan