The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.

Our hypothesis is that even a single dose of paracetamol is sufficient to cause a measurable change in lung functions.

This trial aims to identify a possible effect of single dose paracetamol on lower airway function.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tel-Aviv Sourasky Medical Center
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• age: 7-16 years

• research group: children who have been diagnosed as asthmatic according to the American thoracic society (ATS) criteria

• control group: children who are not known to have asthma

Exclusion Criteria:

• paracetamol sensitivity

• children with any kind of chronic disease (except asthma)

• children with non asthma related chronic lung disease

• acute asthma attack

• children on systemic steroids