The Effect of Sildenafil in Preterm Infants With Evolving Chronic Lung Disease

• Status: Completed
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this pilot study is to investigate in a randomised double-blind trial whether treatment with Sildenafil reduces duration of ventilatory support in preterm infants born at 28 weeks of gestation or less.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mercy Hospital for Women, Australia
• Treatments: Pharmaceutical Solutions; Sildenafil Citrate

Criteria

Inclusion Criteria:

• Newborn babies born <28 weeks of gestation who still need ventilatory support via endotracheal tube or have been re-ventilated at day 7 of life.

Exclusion Criteria:

• Congenital heart defects

• Suspected inborn error of metabolism

• Inhaled Nitric Oxide treatment during assessment