The Effect of Short Term Amiodarone Treatment After Catheter Ablation for Atrial Fibrillation

• Status: Completed
• Trial end date: 2014-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the overall effectiveness of short-time anti-arrhythmic drug treatment with amiodarone (to control heart rhythm) to prevent short-and long-term atrial fibrillation following an ablation procedure for atrial fibrillation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Treatments: Amiodarone

Criteria

Inclusion Criteria:

• Patients with symptomatic paroxysmal or persistent atrial fibrillation undergoing catheter ablation for atrial fibrillation. (persistent episodes may last no more than 12 months)

Exclusion Criteria:

• Contraindication or intolerance to amiodarone.

• Prolonged amiodarone treatment within 3 months before the planned ablation procedure.

• Previous participation in this study.

• Other cardiac arrythmias (patients with co-existing atrial flutter can be included).

• Antiarrhythmic treatment for indication other than atrial fibrillation (or atrial flutter).

• Heart failure (NYHA class III or IV or left ventricular ejection fraction < 35%).

• Significant heart valve disease.

• Significant lung disease, thyroid dysfunction or liver disease.

• Inability or unwillingness to be treated with anticoagulation before and during the study.

• Females with birth giving potential

• Failure to give informed concent.