The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Status:
Enrolling by invitation
Trial end date:
2021-06-20
Target enrollment:
Participant gender:
Summary
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass
into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic
effect according to the density in the brain tissue. All inhalation anesthetics affect organ
functions to varying degrees. Clara cell has been shown to have cell regeneration,
immunomodulatory, anti-inflammatory and antioxidant activity in the bronchial epithelium. It
is also thought that some substances accumulated in the respiratory system participate in the
detoxification. Clara cell protein acts as a protein marker that indicates the severity of
airway injuries after exposure to irritants. In this study, we planned to investigate the
effect of inhalation anesthetics on Clara cell protein in liver transplant donors who will
undergo hepatectomy surgery.