The Effect of Sevoflurane Versus Isoflurane on Vasopressor Need

• Status: Terminated
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: UMC Utrecht
• Treatments: Isoflurane; Sevoflurane; Vasoconstrictor Agents

Criteria

Inclusion Criteria:

• competent adult patients (18 years or older)undergoing elective coronary artery bypass grafting with the use of the cardiopulmonary bypass.

Exclusion Criteria:

• Patients undergoing valve surgery or combined surgical procedures (e.g. coronary artery bypass grafting in combination with valve reconstruction.

• uncontrolled hypertension

• a poor left ventricular function

• renal failure

• a body mass index of > 25

• history of cerebrovascular accident, transient ischemic accident or carotid artery stenosis.