The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
The release of tourniquet produces reactive oxygen species which can cause injury. Propofol
is chemically similar to phenol-based free radical scavengers.
Plasma total antioxidant capacity is a well-established marker of the overall protective
effect of antioxidants in body fluids.The aim of the study is to investigate the effects of
propofol on ischemia-reperfusion injury in total knee arthroplasty (TKA).