Overview

The Effect of Physiotherapy on Post POEM Reflux

Status:
Recruiting
Trial end date:
2024-01-18
Target enrollment:
0
Participant gender:
All
Summary
Per-oral endoscopic myotomy has been used as a treatment method of esophageal achalasia. Patients who undergo POEM as a treatment of achalasia are often presented with development of reflux as a side effect of the surgery. Patients are then in need to use proton pump inhibitor drugs as a long term treatment of the reflux symptoms. Physiotherapy aimed on the strengthening of diaphragm and lower esophageal region is effective in gastroesophageal reflux disease. Therefore we are expecting positive effect of physiotherapy in post POEM patients with reflux symptoms and the possible reduction of PPI drug usage need. The aim of the study is to objectify the effect of physiotherapy, to describe in detail the used physiotherapeutic techniques and to develop practical guidelines for the treatment of patients after POEM with GERD.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Institute for Clinical and Experimental Medicine
Criteria
Inclusion Criteria:

1. esophageal achalasia (or other primary motility disease) treated by per oral
endoscopic myotomy (POEM)

2. symptomatic post-POEM reflux and/or esophagitis LA A/B/C (grade by The Los Angeles
Classification) present 3 months after POEM surgery

3. positive finding on esophageal 24hours pH Test 3 months after POEM surgery

4. signed informed consent

Exclusion Criteria:

1. reflux symptoms previously to the POEM surgery (except regurgitation)

2. repeated POEM surgery

3. Esophagitis of LA grade D

4. asymptomatic pathologic reflux without signs of esophagitis 3 months post POEM surgery
(patient is not indicated to use proton pump inhibitor "PPI" drugs)

5. previous gastric surgery

6. patients undergoing cancer treatment

7. pregnancy

8. known allergy or intolerance of proton pump inhibitor drugs

9. other circumstances preventing participation in the study

10. Inability to obtain informed consent