The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers

• Status: Completed
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: Male

Summary

Placebo responses contribute to medical treatment outcome. The purpose of this study is to determine whether a single intranasal application of oxytocin can increase the placebo response in an experimental model of placebo analgesia in healthy volunteers.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universitätsklinikum Hamburg-Eppendorf
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• healthy volunteers, male and female

• being German-speaking

• Agreeing to participate, verified by completion of informed consent

Exclusion Criteria:

• acute or chronic pain condition

• use of any concomitant medication except contraceptives

• currently pregnant (verified by urine pregnancy test) or lactating

• major mental disorder

• Inability to comply with the study procedures

• abnormal pain sensitivity as indicated by pain threshold

• alcohol intake within last 24 hours