The Effect of Oral Polymeric Diet Enriched With TGF-beta 2 (Modulen) on Clinical Response and Mucosal Healing in Adult Patients With Newly Diagnosed Crohn's Disease

• Status: Not yet recruiting
• Trial end date: 2021-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate prospectively a possible effect of an oral polymeric diet enriched with TGF-beta 2 (Modulen) as compared to Budesonide (one of the commonly accepted treatments for Crohn's disease) on clinical response, mucosal healing and intestinal microbiota in adult patients with newly diagnosed Crohn's disease using a capsule endoscopy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hillel Yaffe Medical Center
• Treatments: Budesonide

Criteria

Inclusion Criteria:

• Newly diagnosed Crohn's Disease

• Mild to moderate severity

Exclusion Criteria:

• Patients who received systemic steroid or Budesonide or biological treatment

• Recent bowel surgery

• Colostomy, ileostomy

• Short bowel syndrome

• Obstructive symptoms

• Pregnancy, lactation

• Cardiac pacemaker or defibrillator

• Swallowing problems

• Uncontrolled metabolic diseases or any other condition that can be exacerbated by steroids