Overview

The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients

Status:
Completed
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
Hyperphosphatemia is common in the peritoneal dialysis population. Current strategies are insufficient to optimize phosphorus control. Animal studies have shown niacinamide, a form of vitamin B, to reduce phosphate uptake by the rat small intestine. Our trial investigates the use of niacinamide, in addition to standard phosphorus lowering strategies, to reduce plasma phosphorus levels in peritoneal dialysis patients versus placebo.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Niacin
Niacinamide
Nicotinic Acids