The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis
Status:
Completed
Trial end date:
2019-12-20
Target enrollment:
Participant gender:
Summary
The proposed study, Hormonal Contraception & BV (HCBV), will investigate the effect of NET-EN
and DMPA on recurrent BV, vaginal microbiota and inflammatory markers among women at high
risk for HIV in Kampala, Uganda. The hypothesis is that NET-EN will show a similar beneficial
effect on recurrent BV and vaginal microbiota as DMPA, without inducing signs of mucosal
inflammation.
Phase:
Phase 4
Details
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborators:
Imperial College London MRC/UVRI and LSHTM Uganda Research Unit MRC/UVRI Uganda Research Unit on Aids University of Liverpool