The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis
Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of nitro-glycerine on the
microcirculation (smallest vessel type) in patients with severe sepsis and septic shock.
Nitro-glycerine is a well known medicine in cardiology and is used to improve circulation. In
this ICU the investigators use nitro-glycerine to improve the organ perfusion; but it's no
common therapy in the rest of the world. The investigators now compare nitro-glycerine and
placebo by looking to the sublingual microcirculation by a small camera (SDF imaging).