Overview

The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker

Status:
Unknown status
Trial end date:
2010-10-01
Target enrollment:
0
Participant gender:
All
Summary
1. Treatment of Hypercholesterolemic patients with niacin will cause a significant decrease in oxidative stress and a decrease in the atherogenecity in blood samples of the patients. 2. A possible correlation between oxidative stress in hypercholesterolemic patients taking niacin to clinical hypercholesterolemia parameters is possible. 3. Using a novel biomarker will enable a precise detection of the change in the oxidative stress in hypercholesterolemic patients.
Phase:
Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Rambam Health Care Campus
Treatments:
Niacin
Niacinamide
Nicotinic Acids
Criteria
Inclusion Criteria:

- Hypercholesterolemia,

- age above eighteen

Exclusion Criteria:

- Treatment with fibrates,

- Pregnant/Breast feeding women