The Effect of Nebulized Albuterol on Donor Oxygenation
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the effectiveness of albuterol versus placebo with the
following specific aims: a) Treatment of brain dead organ donors with albuterol will reduce
pulmonary edema, improve donor oxygenation, and increase the number of lungs available for
transplantation, b) Developing a blood test to predict the development of primary graft
dysfunction in lung transplant recipients, and c) treating brain dead organ donors with
albuterol will decrease markers of primary graft dysfunction and lead to improved lung
transplant recipient outcomes and to higher rates of lungs suitable for transplantation.
Phase:
Phase 2
Details
Lead Sponsor:
Vanderbilt University Medical Center
Collaborators:
California Transplant Donor Network University of California, San Francisco