The Effect of Nasal Carbon Dioxide (CO2) on Nasal Congestion in Subjects With Perennial Allergic Rhinitis

• Status: Completed
• Trial end date: 2008-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effect of nasal CO2 on nasal congestion and other symptoms related to Perennial Allergic Rhinitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Capnia, Inc.

Criteria

Inclusion Criteria:

• Have a history consistent with minimal 2 year history of perennial allergic rhinitis requiring pharmacotherapy.

• Positive skin test to perennial allergens (e.g. cats, dogs, house dust mite, etc.)

• Females of childbearing potential must commit to using an acceptable method of birth control and have a negative pregnancy test

Exclusion Criteria:

• History of asthma (other than mild or intermittent)

• Clinically significant nasal disorders

• Acute or significant sinusitis or upper respiratory infection within 14 days of randomization

• Have an existing serious medical condition (such as severe emphysema, other respiratory diseases, heart disease, etc.) that precludes participation in the study

• Use of certain medication s prior to randomization and during study participation

• Participation in prior study with Nasal CO2

• Participation in another clinical study within 30 days of planned randomization date and for the duration of the study