Overview

The Effect of N115 on Coughing in IPF Patients

Status:
COMPLETED
Trial end date:
2024-05-20
Target enrollment:
Participant gender:
Summary
The purpose of this clinical trial is to administer a sodium pyruvate nasal spray that eliminates nasal oxidative stresses, caused by oxygen radicals, and demonstrate the efficacy of sodium pyruvate to reduce coughing and increase lung functions in patients with idiopathic pulmonary fibrosis. This will be a 21-day double-blinded randomized placebo-controlled trial designed to determine if patients with idiopathic pulmonary fibrosis treated with 20mM sodium pyruvate in 0.9% sodium chloride nasal spray solution will have reduced chronic coughing, as well as increased lung function (FEV1, FVC endpoints of 12% or more within the first week) and improved FEV1/FVC ratios.
Phase:
PHASE3
Details
Lead Sponsor:
Cellular Sciences, inc.
Collaborator:
Family First Medical Research Center