Overview

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Status:
Completed
Trial end date:
2019-12-30
Target enrollment:
0
Participant gender:
All
Summary
The effect of N-acetylcysteine as antioxidant and its effect on pretransfusion hemoglobin and iron overload in patients with thalassemia were compared to patients who didn't receive n-acetylcysteine after 3 months of study duration
Phase:
Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Beni-Suef University
Treatments:
Acetylcysteine
N-monoacetylcystine
Criteria
Inclusion Criteria:

- Thalassemia major children on regular blood transfusion and iron chelation therapy

Exclusion Criteria:

- Renal or hepatic impairments

- Complicated thalassemia major

- Non adherence to therapy or follow up visits

- Change in the iron chelation dose within 3 months before enrollment or during study
period